Tunable, pulsatile chemical gradient generation via acoustically driven oscillating bubbles.
نویسندگان
چکیده
We present a novel concept of generating both static and pulsatile chemical gradients using acoustically activated bubbles designed in a ladder-like arrangement. Furthermore, by regulating the amplitude of the bubble oscillation, we demonstrate that the chemical gradient profiles can be effectively tuned.
منابع مشابه
A spatiotemporally controllable chemical gradient generator via acoustically oscillating sharp-edge structures.
The ability to generate stable, spatiotemporally controllable concentration gradients is critical for resolving the dynamics of cellular response to a chemical microenvironment. Here we demonstrate an acoustofluidic gradient generator based on acoustically oscillating sharp-edge structures, which facilitates in a step-wise fashion the rapid mixing of fluids to generate tunable, dynamic chemical...
متن کاملDestruction of Recombinant Tissue Plasminogen Activator (rtPA) -Loaded Echogenic Liposomes under Dual Frequency Sonication
Background:Echogenic liposomes (ELIPs) encapsulate drugs and gas bubbles within lipid vesicles. The destruction of ELIPs in response to MHz and kHz ultrasound waves has been studied previously. Applying ultrasound above a certain threshold causes encapsulated gas bubbles destruct rapidly by fragmentation or more slowly by acoustically driven diffusion. This study compares the d...
متن کاملTurbulent Pulsatile Pipe Flow with Multiple Modes of Oscillation
This study numerically investigates turbulent pipe flow driven by a pulsating pressure gradient. While studies of laminar and turbulent pulsatile pipe flow with a single mode of oscillating pressure gradient have been carried out extensively, there is scarce literature on pulsating pressure gradients with multiple temporal Fourier modes. In many real-life engineering applications, for example, ...
متن کاملStudy on the bubble transport mechanism in an acoustic standing wave field.
The use of bubbles in applications such as surface chemistry, drug delivery, and ultrasonic cleaning etc. has been enormously popular in the past two decades. It has been recognized that acoustically-driven bubbles can be used to disturb the flow field near a boundary in order to accelerate physical or chemical reactions on the surface. The interactions between bubbles and a surface have been s...
متن کاملAcoustically driven programmable liquid motion using resonance cavities.
Performance and utility of microfluidic systems are often overshadowed by the difficulties and costs associated with operation and control. As a step toward the development of a more efficient platform for microfluidic control, we present a distributed pressure generation scheme whereby independently tunable pressure sources can be simultaneously controlled by using a single acoustic source. We...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Lab on a chip
دوره 13 3 شماره
صفحات -
تاریخ انتشار 2013